1,10‐Phenanthroline: A versatile ligand to promote copper‐catalyzed cascade reactions
Fengtian Wu, Jianwei Xie, Zhiqiang Zhu
Abstract
Ligand‐promoted copper‐catalyzed cascade reactions have become a robust tool for the synthesis of cyclic compounds. Although numerous ligands have been developed, this review focuses on the introduction of commercially available 1,10‐phenanthroline‐promoted copper‐catalyzed cascade reactions in recent years. Moreover, based on original articles, this review highlights product yields in the presence and absence of the ligand, and the possible mechanistic role of the ‘copper/1,10‐phenanthroline’ catalytic system.
Topics & Concepts
ChemistryCascadeCopperLigand (biochemistry)PhenanthrolineCatalysisCombinatorial chemistryOrganic chemistryReceptorChromatographyBiochemistryCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsCatalytic Cross-Coupling Reactions