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Time-resolved cryo-EM of G-protein activation by a GPCR

Makaía M. Papasergi-Scott, Guillermo Pérez‐Hernández, Hossein Batebi, Yang Gao, Gözde Eskici, Alpay B. Seven, Ouliana Panova, Daniel Hilger, Marina Casiraghi, Feng He, Luis Maul, Peter Gmeiner, Brian K. Kobilka, Peter W. Hildebrand, Georgios Skiniotis

2024Nature125 citationsDOIOpen Access PDF

Topics & Concepts

G protein-coupled receptorHeterotrimeric G proteinG proteinGTPaseBiophysicsGTP'Protein structureHelix (gastropod)ChemistryGuanine nucleotide exchange factorBiologyReceptorCell biologyBiochemistrySnailEcologyEnzymeReceptor Mechanisms and SignalingMass Spectrometry Techniques and ApplicationsProtein Structure and Dynamics
Time-resolved cryo-EM of G-protein activation by a GPCR | Litcius