Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study
Chung‐Han Lee, Amishi Y. Shah, Drew Rasco, Arpit Rao, Matthew H. Taylor, Christopher Di Simone, James J. Hsieh, Álvaro Pinto, David R. Shaffer, Regina Gironés Sarrió, Allen Lee Cohn, Nicholas J. Vogelzang, Mehmet Asım Bilen, Sara Gunnestad Ribe, Musaberk Goksel, Øyvind Tennøe, Donald Richards, Randy F. Sweis, Jay Courtright, Daniel Heinrich, Sharad Jain, Jane Wu, Emmett V. Schmidt, Rodolfo F. Perini, Peter Kubiak, Chinyere E. Okpara, Alan D. Smith, Robert J. Motzer
Topics & Concepts
PembrolizumabLenvatinibMedicineRenal cell carcinomaInternal medicineOncologyClinical endpointNivolumabExpanded accessClinical trialPhases of clinical researchAdverse effectImmunotherapyCancerThyroid cancerRenal cell carcinoma treatmentCancer Immunotherapy and BiomarkersFerroptosis and cancer prognosis