Developing novel zinc(<scp>ii</scp>) and copper(<scp>ii</scp>) Schiff base complexes: combined experimental and theoretical investigation on their DNA/protein binding efficacy and anticancer activity
Manik Das, Somali Mukherjee, Biplab Koley, Indranil Choudhuri, Nandan Bhattacharyya, Pritam Roy, Bidhan Chandra Samanta, Manas Barai, Tithi Maity
Abstract
Zn(<sc>ii</sc>) and Cu(<sc>ii</sc>) Schiff base complexes having DNA and HSA binding efficacy have been exploited as cancer therapeutic agents.
Topics & Concepts
ChemistrySchiff baseCopperDNAZincCombinatorial chemistryBiochemistryStereochemistryOrganic chemistryMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds