Epicatechin-assembled nanoparticles against renal ischemia/reperfusion injury
Jianhua Zhang, Huixu Xie, Tianyou Wang, Hengjie Zhang, Zhen Yang, Peng Yang, Yiwen Li, Xuelei Ma, Zhipeng Gu
Abstract
. Furthermore, in the renal ischemia/reperfusion model, blood renal function testing and renal tissue staining revealed a prominent therapeutic effect of PEC NPs. All these findings suggested that this class of bioinspired antioxidant nanoparticles provided a new therapeutic strategy for human ischemia/reperfusion-related diseases.
Topics & Concepts
Oxidative stressAntioxidantPharmacologyNanoparticleRenal ischemiaReperfusion injuryAcute kidney injuryIn vitroMaterials scienceIschemiaChemistryNanotechnologyMedicineBiochemistryInternal medicineAdvanced Nanomaterials in CatalysisNanoparticles: synthesis and applicationsNanoplatforms for cancer theranostics