A cell membrane-targeting AIE photosensitizer as a necroptosis inducer for boosting cancer theranostics
Niu Niu, Ying Yu, Zhijun Zhang, Miaomiao Kang, Lei Wang, Zheng Zhao, Dong Wang, Ben Zhong Tang
Abstract
A membrane-targeting photosensitizer TBMPEI with AIE properties was synthesized via a new acceptor, and it was utilized as a necroptosis inducer during imaging-guided photodynamic therapy.
Topics & Concepts
PhotosensitizerNecroptosisPhotodynamic therapyCancer cellChemistryReactive oxygen speciesBiophysicsIn vivoOrganelleProgrammed cell deathCancerPhotochemistryApoptosisBiochemistryBiologyBiotechnologyGeneticsOrganic chemistryNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced biosensing and bioanalysis techniques