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Analysis of mutation status and homologous recombination deficiency in tumors of patients with germline BRCA1 or BRCA2 mutations and metastatic breast cancer: OlympiAD

Darren Hodgson, Zhongwu Lai, Simon Dearden, J. Carl Barrett, Elizabeth A. Harrington, Kirsten M. Timms, Jerry S. Lanchbury, Weiwen Wu, A. Allen, Elżbieta Senkus, Susan M. Domchek, Mark E. Robson

2021Annals of Oncology43 citationsDOIOpen Access PDF

Topics & Concepts

MedicineBreast cancerLoss of heterozygosityGermlineOncologyPARP inhibitorInternal medicineOlaparibMetastatic breast cancerGermline mutationCancerBRCA mutationCancer researchMutationAllelePoly ADP ribose polymerasePolymeraseGeneticsGeneBiologyPARP inhibition in cancer therapyBRCA gene mutations in cancerAdvanced Breast Cancer Therapies
Analysis of mutation status and homologous recombination deficiency in tumors of patients with germline BRCA1 or BRCA2 mutations and metastatic breast cancer: OlympiAD | Litcius