Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition
Jennifer Tang, Hong Shen, Xiaofeng Zhao, Vinay K. Holenarsipur, T. Thanga Mariappan, Yueping Zhang, Erika Panfen, Jim Zheng, W. Griffith Humphreys, Yurong Lai
Topics & Concepts
ProbenecidKynurenic acidChemistryFurosemideXanthurenic acidPharmacologyOrganic anion transporter 1TransporterBiochemistryAmino acidMedicineTryptophanGeneOrganic chemistryTryptophan and brain disordersDrug Transport and Resistance MechanismsPharmacological Effects and Toxicity Studies