Irinotecan and berberine co-delivery liposomes showed improved efficacy and reduced intestinal toxicity compared with Onivyde for pancreatic cancer
Xue Wang, Ying Liu, Wanjia Xu, Lirui Jia, Dongxu Chi, Jiang Yu, Jiamei Wang, Zhonggui He, Xiaohong Liu, Yongjun Wang
Topics & Concepts
IrinotecanBerberinePharmacokineticsPancreatic cancerPharmacologyLiposomeToxicityCamptothecinDistribution (mathematics)MedicineBiodistributionChemistryCancerInternal medicineColorectal cancerIn vitroBiochemistryMathematicsMathematical analysisBerberine and alkaloids researchCancer therapeutics and mechanismsDrug Transport and Resistance Mechanisms