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Cytokine-induced killer (CIK) cells, successes and challenges: report on the first international conference dedicated to the clinical translation of this unique adoptive cell immunotherapy

Amit Sharma, Xiubao Ren, Antonio Rosato, Dario Sangiolo, Zibing Wang, Sarah Tettamanti, Yi Zhang, Eva Rettinger, Kevin Fenix, Roberta Sommaggio, Elisa Cappuzzello, Ingo G.H. Schmidt‐Wolf

2024Cancer Immunology Immunotherapy15 citationsDOIOpen Access PDF

Abstract

On August 30, 2023, experts from Germany and abroad met to discuss the successes and challenges of cytokine-induced killer cell (CIK) therapy, that recently celebrated its 30th anniversary providing treatment for cancer. This first virtual conference was hosted by CIO Bonn, a certified Comprehensive Cancer Center (CCC) funded by German Cancer Aid (DKH). In addition to keynote speakers involved in CIK cell clinical trials or optimized preclinical models to improve this adoptive cell immunotherapy, more than 100 attendees from around the world also participated in this event. Initiatives to establish the International Society of CIK Cells (ISCC) and a stronger CIK cell network guiding preclinical research and future clinical trials were also announced.

Topics & Concepts

ImmunotherapyMedicineCytokine-induced killer cellAdoptive immunotherapyClinical trialCancer immunotherapyCell therapyCancerImmunologyCellInternal medicineImmune systemCD8BiologyGeneticsCD3CAR-T cell therapy researchImmune Cell Function and InteractionCancer Immunotherapy and Biomarkers