A large Stokes shift NIR fluorescent probe for visual monitoring of mitochondrial peroxynitrite during inflammation and ferroptosis and in an Alzheimer's disease model
Shiying Chen, Wei Huang, Hongli Tan, Guoxing Yin, Shengyou Chen, Kuicheng Zhao, Yinghui Huang, Youyu Zhang, Haitao Li, Cuiyan Wu
Abstract
A mitochondria-targeted near-infrared fluorescent probe was developed for selective and sensitive detection of ONOO − both in vitro and in vivo .
Topics & Concepts
PeroxynitriteInflammationFluorescenceDiseaseBiophysicsChemistryMedicineBiologyBiochemistryPathologyPhysicsImmunologyOpticsSuperoxideEnzymeSulfur Compounds in BiologyMolecular Sensors and Ion DetectionAdvanced Nanomaterials in Catalysis