Tracking endoplasmic reticulum viscosity during ferroptosis and autophagy using a molecular rotor probe
Akshay Silswal, Apurba Lal Koner
Abstract
We have designed and synthesized a viscosity-sensitive, far-red emissive, ER-selective, and molecular rotor probe JER to monitor the ER fate during ferroptosis and ER-phagy processes.
Topics & Concepts
Endoplasmic reticulumViscosityRotor (electric)AutophagyTracking (education)ChemistryCell biologyBiophysicsNanotechnologyMaterials scienceBiologyBiochemistryElectrical engineeringEngineeringPsychologyComposite materialApoptosisPedagogyPorphyrin and Phthalocyanine ChemistryMolecular Sensors and Ion DetectionSulfur Compounds in Biology