Multi-omics characterization of molecular features of gastric cancer correlated with response to neoadjuvant chemotherapy
Ziyu Li, Xiangyu Gao, Xinxin Peng, Mei-Ju May Chen, Zhe Li, Bin Wei, Xianzi Wen, Baoye Wei, Dong Yu, Zhaode Bu, Aiwen Wu, Qi Wu, Lei Tang, Zhongwu Li, Yiqiang Liu, Li Zhang, Shuqin Jia, Lianhai Zhang, Fei Shan, Ji Zhang, Xiaojiang Wu, Xin Ji, Ke Ji, Xiaolong Wu, Jinyao Shi, Xiaofang Xing, Jianmin Wu, Guoqing Lv, Lin Shen, Xuwo Ji, Han Liang, Jiafu Ji
Abstract
amplification showed the opposite pattern. Neoadjuvant chemotherapy also reshapes tumor-immune signaling and microenvironment. Our study provides a critical basis for developing precision neoadjuvant regimens.
Topics & Concepts
ChemotherapyCancerOmicsNeoadjuvant therapyMedicineBioinformaticsComputational biologyOncologyCancer researchBiologyInternal medicineBreast cancerGastric Cancer Management and OutcomesColorectal Cancer Treatments and StudiesCholangiocarcinoma and Gallbladder Cancer Studies