Silyloxymethanesulfinate as a sulfoxylate equivalent for the modular synthesis of sulfones and sulfonyl derivatives
Dae‐Kwon Kim, Hyun‐Suk Um, Hoyoon Park, Seonwoo Kim, Jin Ho Choi, Chulbom Lee
Abstract
-arylation reactions with alkyl and aryl electrophiles. The sulfone products thus obtained can undergo the second bond formation at the sulfur center with various electrophiles without a separate unmasking step to afford sulfones and sulfonyl derivatives such as sulfonamides and sulfonyl fluorides.
Topics & Concepts
SulfonylModular designSulfoneChemistrySodiumCombinatorial chemistryMedicinal chemistryOrganic chemistryComputer scienceProgramming languageAlkylSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsRadical Photochemical Reactions