Roles of the Microbiota of the Female Reproductive Tract in Gynecological and Reproductive Health
Bin Zhu, Zhi Tao, Laahirie Edupuganti, Myrna G. Serrano, Gregory A. Buck
Abstract
is generally associated with health, whereas vaginal microbiomes consisting of other taxa are generally associated with dysbiosis and a higher risk of disease. The past decade has seen a rapid advancement in our understanding of these unique biosystems. Of particular interest, substantial effort has been devoted to deciphering how members of the microbiome of the female reproductive tract impact pregnancy, with a focus on adverse outcomes, including but not limited to preterm birth. Herein, we review recent research efforts that are revealing the mechanisms by which these microorganisms of the female reproductive tract influence gynecologic and reproductive health of the female reproductive tract.