The modified outer membrane protein Amuc_1100 of <i>Akkermansia muciniphila</i> improves chronic stress-induced anxiety and depression-like behavior in mice
Rongrong Cheng, Haiyan Zhu, Sun Yan, Tianrong Hang, Min Zhang
Abstract
and its outer membrane protein Amuc_1100 but also identifies new potential targets and pathways in the gut for future research and the development of antidepressant drugs.
Topics & Concepts
Akkermansia muciniphilaDownregulation and upregulationAkkermansiaTLR2Internal medicineEndocrinologyBacterial outer membraneChemistryReceptorCell biologyGut floraBiologyMedicineBiochemistryTLR4LactobacillusEscherichia coliGeneFermentationTryptophan and brain disordersGut microbiota and healthStress Responses and Cortisol