Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosis
José Raphael Monteiro Neto, Gabriela Delaqua Ribeiro, Rayne Stfhany Silva Magalhães, Cristian Follmer, Tiago F. Outeiro, Elis C. A. Eleuthério
Topics & Concepts
GlycationAmyotrophic lateral sclerosisSOD1MethylglyoxalOxidative stressSuperoxide dismutaseToxicityBiochemistryChemistryReactive oxygen speciesOxidative phosphorylationCell biologyBiologyInternal medicineDiseaseEnzymeMedicineOrganic chemistryReceptorAmyotrophic Lateral Sclerosis ResearchParkinson's Disease Mechanisms and Treatmentsbiodegradable polymer synthesis and properties