Litcius/Paper detail

Clinical significance of MDRO screening and infection risk factor analysis in the ICU.

Yan Zhou, Fan Yu, Ying Yu, Yiduo Zhang, Yongmei Jiang

2021PubMed27 citationsOpen Access PDF

Abstract

OBJECTIVE: This study aimed to investigate the clinical significance of multi-drug resistant organism (MDRO) screening and infection risk factor analysis in the intensive care unit (ICU). METHOD: A total of 210 patients treated in the ICU of our hospital were enrolled as the study subjects, and were divided into the MDRO group (n=100 cases) and the non-MDRO group (n=110) according to the presence or absence of MDRO infection after examination of the pharyngeal swabs. The pathogens of MDRO infection and drug resistance were analyzed. The single-factor as well as multifactor logistic regression analysis of MDRO infections were carried out and the 30-d mortality rate, hospitalization time and treatment costs were compared between the two groups. RESULTS: <0.05). CONCLUSION: ICU mechanical ventilation, arterial and intravenous intubation, fiberoptic bronchoscopy, concurrent chronic lung disease and chronic cardiovascular disease are the independent risk factors for MDRO infection.

Topics & Concepts

MedicineMechanical ventilationIntensive care unitLogistic regressionRisk factorTracheotomyIntubationVancomycinInternal medicineAnesthesiaIntensive care medicineStaphylococcus aureusBiologyGeneticsBacteriaNosocomial Infections in ICUAntibiotic Use and ResistanceSepsis Diagnosis and Treatment