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PFOA exposure induces aberrant glucose and lipid metabolism in the rat liver through the AMPK/mTOR pathway

Xuemin Zhang, Xijuan Ren, Weiqiang Sun, Nathan Griffin, Li Wang, Hui Liu

2023Toxicology41 citationsDOI

Topics & Concepts

Perfluorooctanoic acidAMPKLipid metabolismMetabolismPI3K/AKT/mTOR pathwayToxicityBlotCarbohydrate metabolismMetabolomicsChemistryWestern blotEndocrinologyInternal medicineBiologyBiochemistrySignal transductionMedicineProtein kinase AKinaseBioinformaticsGenePer- and polyfluoroalkyl substances researchCancer, Hypoxia, and MetabolismAdipose Tissue and Metabolism
PFOA exposure induces aberrant glucose and lipid metabolism in the rat liver through the AMPK/mTOR pathway | Litcius