Chalcogen functionalized pyrimidine synthesis by three-component free radical chalcogenation and pyrimidine ring construction
Jingfeng Ye, Guangli Li, Changfeng Wan, Jie‐Ping Wan
Abstract
The synthesis of 5-chalcogenated pyrimidines has been achieved via one-step, three-component reactions through cascade C–H chalcogenation and pyrimidine ring construction under transition metal-free conditions.
Topics & Concepts
ChemistryPyrimidineChalcogenRing (chemistry)CascadeStereochemistryCombinatorial chemistryPyrimidine analogueSubstitution (logic)Polymer chemistrySulfur-Based Synthesis TechniquesSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds