From main-chain conjugated polymer photosensitizer to hyperbranched polymer photosensitizer: expansion of the polymerization-enhanced photosensitization effect for photodynamic therapy
Jingxi Cheng, Yuping Zhou, Shidang Xu, Yujun Xie, Duo Mao, Wenbo Wu, Zhen Li
Abstract
A donor–acceptor-type hyperbranched polymer was firstly designed to show both highly efficient Type-I and Type-II photosensitization effects, and has been successfully used for photodynamic therapy with better efficacy than hemoporfin.
Topics & Concepts
PhotosensitizerPhotodynamic therapyConjugated systemPolymerMaterials sciencePolymerizationPhotochemistryAcceptorPolymer chemistryChemistryOrganic chemistryComposite materialPhysicsCondensed matter physicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies