Gel@CAT-L hydrogel mediates mitochondrial unfolded protein response to regulate reactive oxygen species and mitochondrial homeostasis in osteoarthritis
Jiajia Lu, Jiao Cai, Zhibin Zhou, Jun Ma, Tianyu Han, Nan Lü, Lei Zhu, Lei Zhu
Topics & Concepts
Reactive oxygen speciesUnfolded protein responseHomeostasisMitochondrionCell biologyOsteoarthritisMaterials scienceBiophysicsBiologyMedicineEndoplasmic reticulumPathologyAlternative medicineOsteoarthritis Treatment and MechanismsProtein Degradation and InhibitorsHydrogels: synthesis, properties, applications