SPARC promotes fibroblast proliferation, migration, and collagen production in keloids by inactivation of p53
Shanshan Shi, Qiuchen Li, Yanxin Liu, Rui Zhang, Huaxia Chen
Topics & Concepts
KeloidFibroblastFibronectinGene knockdownOsteonectinExtracellular matrixWound healingBlotCell migrationCell growthChemistryCancer researchDownregulation and upregulationMolecular biologyCell biologyCellBiologyPathologyMedicineImmunologyApoptosisGeneIn vitroBiochemistryEnzymeAlkaline phosphataseOsteocalcinBone and Dental Protein StudiesDermatologic Treatments and ResearchBone health and treatments