A Bottom-Up Coarse-Grained Model for Nucleosome–Nucleosome Interactions with Explicit Ions
Tiedong Sun, Vishal Minhas, Alexander Mirzoev, Nikolay Korolev, Alexander P. Lyubartsev, Lars Nordenskiöld
Abstract
) for systems comprising 20 NCPs. The results of the simulations reveal structural details of the NCP-NCP interactions unavailable from experimental approaches, and this model opens the prospect for the rigorous modeling of chromatin fibers.
Topics & Concepts
NucleosomeComputer scienceIonChemistryHistoneDNABiochemistryOrganic chemistryDNA and Nucleic Acid ChemistryBacteriophages and microbial interactionsAdvanced biosensing and bioanalysis techniques