Hybrids of polyphenolic acids and xanthone, the potential preventive and therapeutic effects on PD: Design, synthesis, in vitro anti-aggregation of α-synuclein, and disaggregation against the existed α-synuclein oligomer and fibril
Feng Han, Bing Jiang, Ming-Huan Lü, Zhenping Wang, Wei Liu, Yunxiao Zhang, Ji Xu
Topics & Concepts
ChemistryFibrilOligomerProteostasisProtein aggregationXanthoneIn vitroBiophysicsStereochemistryBiochemistryOrganic chemistryBiologyParkinson's Disease Mechanisms and TreatmentsGinkgo biloba and Cashew ApplicationsAlzheimer's disease research and treatments