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Advantages, applications, and future directions of in vivo aptamer SELEX: A review

Minchuan Lyu, Chi Ho Chan, Ziqi Chen, Yumeng Liu, Yuanyuan Yu

2025Molecular Therapy — Nucleic Acids23 citationsDOIOpen Access PDF

Abstract

SELEX in various fields, including neurology, oncology, and cardiovascular diseases, and provides insights into future directions for optimizing this technology.

Topics & Concepts

AptamerSystematic evolution of ligands by exponential enrichmentComputational biologyNanotechnologyComputer scienceBiochemical engineeringBiologyEngineeringMaterials scienceGeneticsRNAGeneAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry
Advantages, applications, and future directions of in vivo aptamer SELEX: A review | Litcius