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A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy

Jiali Chen, Xinxin Wang, Lei Chen, Jie Tang, Yunfei Xia, Ke Qian, Zheng‐Hong Qin, Christian Waeber, Rui Sheng

2020Neuropharmacology24 citationsDOIOpen Access PDF

Topics & Concepts

NeuroprotectionMitophagyPharmacologyIschemiaReperfusion injuryChemistrySphingosine kinaseCell biologyApoptosisMedicineAutophagySphingosineBiologyBiochemistryInternal medicineReceptorSphingosine-1-phosphateAutophagy in Disease and TherapySphingolipid Metabolism and SignalingNeuroinflammation and Neurodegeneration Mechanisms
A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy | Litcius