Litcius/Paper detail

TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma

Daisuke Ennishi, Shannon Healy, Ali Bashashati, Saeed Saberi, Christoffer Hother, Anja Mottok, Fong Chun Chan, Lauren C. Chong, Libin Abraham, Robert Kridel, Merrill Boyle, Barbara Meissner, Tomohiro Aoki, Katsuyoshi Takata, Bruce W. Woolcock, Elena Viganò, Michael R. Gold, Laurie L. Molday, Robert S. Molday, Adèle Telenius, Michael Y. Li, Nicole Wretham, Nancy Dos Santos, Mark Wong, Natasja Nielsen Viller, Robert A. Uger, Gerben Duns, Abigail Baticados, Angel M. Madero, Brianna N. Bristow, Pedro Farinha, Graham W. Slack, Susana Ben‐Neriah, Daniel Lai, Allen W. Zhang, Sohrab Salehi, Hennady P. Shulha, Derek S. Chiu, Sara Mostafavi, Alina S. Gerrie, Da Wei Huang, Christopher Rushton, Diego Villa, Laurie H. Sehn, Kerry J. Savage, Andrew J. Mungall, Andrew P. Weng, Marcel B. Bally, Ryan D. Morin, Gabriela V. Cohen Freue, Louis M. Staudt, Joseph M. Connors, Marco A. Marra, Sohrab P. Shah, Randy D. Gascoyne, David W. Scott, Christian Steidl

2020Nature Medicine80 citationsDOIOpen Access PDF

Topics & Concepts

LymphomaVulnerability (computing)Function (biology)Cancer researchLoss functionBiologyMutationGeneticsImmunologyGeneComputer sciencePhenotypeComputer securitySignaling Pathways in DiseaseChronic Lymphocytic Leukemia ResearchCAR-T cell therapy research
TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma | Litcius