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Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry

Andrew Jordan, Patrick Stoy, Helen F. Sneddon

2020Chemical Reviews159 citationsDOIOpen Access PDF

Abstract

Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.

Topics & Concepts

ChemistryBiochemical engineeringEnvironmental chemistryChlorinated solventsOrganic chemistryNanotechnologyContaminationBiologyEngineeringMaterials scienceEcologyChemistry and Chemical EngineeringInorganic and Organometallic ChemistryChemical Synthesis and Reactions