Litcius/Paper detail

Discovery of higenamine as a potent, selective and cellular active natural LSD1 inhibitor for MLL-rearranged leukemia therapy

Yuan Fang, Chao Yang, Dehong Teng, Shiwei Su, Xiang Luo, Zhongqiu Liu, Guochao Liao

2021Bioorganic Chemistry23 citationsDOI

Topics & Concepts

ChemistryLeukemiaEpigeneticsK562 cellsApoptosisCD86Cancer researchBiochemistryBiologyGeneImmunologyPhenotypeEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Discovery of higenamine as a potent, selective and cellular active natural LSD1 inhibitor for MLL-rearranged leukemia therapy | Litcius