Design of graphenic nanocomposites containing chitosan and polyethylene glycol for spinal cord injury improvement
Ayda Yari-Ilkhchi, Abbas Ebrahimi‐Kalan, Mehdi Farhoudi, Mehrdad Mahkam
Abstract
study on mesenchymal stem cells (MSCs) has demonstrated that the prepared nanocomposites are not only non-toxic but also increase (by nearly 10%) cell growth. Finally, the use of mixed nanocomposites in the spinal cord injury (SCI) model resulted in good repair and inflammation decline after two weeks, such that walking and functional recovery scores of the hind limbs of mice were improved by an average of 6 points in the treatment group.
Topics & Concepts
ChitosanPolyethylene glycolNanocompositeSpinal cord injuryPolyethyleneMaterials scienceSpinal cordChemistryComposite materialOrganic chemistryMedicinePsychiatryGraphene and Nanomaterials ApplicationsScientific and Engineering Research TopicsElectrospun Nanofibers in Biomedical Applications