Target-driven supramolecular self-assembly for selective amyloid-β photooxygenation against Alzheimer's disease
Zhenqi Liu, Mengmeng Ma, Dongqin Yu, Jinsong Ren, Xiaogang Qu
Abstract
Photo-oxygenation of β-amyloid (Aβ) has been considered an efficient way to inhibit Aβ aggregation in Alzheimer's disease (AD). We present the first example of Aβ-responsive photodynamic therapy to treatment of AD by using PKNPs self-assemblies.
Topics & Concepts
PhotooxygenationAmyloid (mycology)DiseaseAmyloid βSupramolecular chemistryChemistryPhotodynamic therapyβ amyloidAlzheimer's diseaseNeuroscienceMedicineBiologyInternal medicinePathologyMoleculeSinglet oxygenOrganic chemistryOxygenSupramolecular Self-Assembly in MaterialsAlzheimer's disease research and treatmentsNanoplatforms for cancer theranostics