Nanoparticles that target the mitochondria of tumor cells to restore oxygen supply for photodynamic therapy: Design and preclinical validation against breast cancer
Xiaosheng Bai, Yan Lin, Lingyi Gong, Junfeng Duan, Xiaoduan Sun, Changguang Wang, Zerong Liu, Zerong Liu, Jun Jiang, Xiangyu Zhou, Meiling Zhou, Zhirong Zhang, Zhongbing Liu, Zhongbing Liu, Jing Pei, Zhirong Zhong
Topics & Concepts
Photodynamic therapyPhotosensitizerChemistryReactive oxygen speciesCancer researchConjugateCancer cellIn vivoMitochondrionTumor microenvironmentBiophysicsCancerPharmacologyMedicineBiochemistryBiologyInternal medicineTumor cellsMathematicsBiotechnologyOrganic chemistryMathematical analysisNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer, Hypoxia, and Metabolism