Core–multi-shell design: unlocking multimodal capabilities in lanthanide-based nanoparticles as upconverting, <i>T</i><sub>2</sub>-weighted MRI and CT probes
Nan Liu, Christian Homann, Samuel Morfin, Meghana S. Kesanakurti, Nicholas D. Calvert, Adam J. Shuhendler, Tom A. Al, Eva Hemmer
Abstract
Core/shell/shell nanoparticle design with a controlled inner NaGdF 4 layer between the upconverting Er/Yb-doped NaGdF 4 core and the magnetic NaDyF 4 shell suppressed Dy 3+ -induced emission loss, while simultaneously enhancing MRI T 2 and CT performance.
Topics & Concepts
LanthanideShell (structure)Materials scienceNanoparticleCore (optical fiber)Inner coreNanotechnologyDopingLayer (electronics)Nuclear magnetic resonanceOptoelectronicsPhysicsComposite materialIonQuantum mechanicsLuminescence Properties of Advanced MaterialsAtomic and Subatomic Physics ResearchLanthanide and Transition Metal Complexes