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New Approach for a Highly Sensitive V-Shaped SPR Biosensor for a Wide Range of Analyte RI Detection

Md Abu Huraiya, S. M. Abdur Razzak, Hitoshi Tabata, Sankar Ganesh Ramaraj

2024The Journal of Physical Chemistry C33 citationsDOI

Abstract

We present a novel and straightforward design for a photonic crystal fiber (PCF)-based surface plasmon resonance sensor suitable for a wide range of sensing applications. The sensor’s performance is numerically analyzed using the finite element method implemented in COMSOL Multiphysics software. Our numerical results demonstrate a wavelength sensitivity(WS) of 88,000 nm/RIU and an amplitude sensitivity(AS) of 3136 RIU –1, with a resolution of 1.136 × 10 –6 RIU. The proposed sensor is capable of detecting analytes within the refractive index (RI) range of 1.29–1.44. Additionally, we investigate the sensor’s fabrication tolerance concerning variations in pitch, air-hole diameter, and channel size, and it exhibits good tolerance to these variations. The sensor also demonstrates a high figure of merit of 1517. With its high sensitivity, broad sensing capability, and excellent fabrication tolerance, this sensor is highly versatile for detecting a wide range of analytes, including glucose, cholesterol, and hemoglobin, making it suitable for various biological and biochemical applications.

Topics & Concepts

AnalyteBiosensorMaterials scienceChromatographyNanotechnologyChemistryAdvanced biosensing and bioanalysis techniquesPlasmonic and Surface Plasmon ResearchAcoustic Wave Resonator Technologies
New Approach for a Highly Sensitive V-Shaped SPR Biosensor for a Wide Range of Analyte RI Detection | Litcius