The novel SOD mimetic GC4419 increases cancer cell killing with sensitization to ionizing radiation while protecting normal cells
Mohamed Elmahdy, Yasmin A. Alzarie, Craig Hemann, Osama A. Badary, Shahira Nofal, Jay L. Zweíer
Topics & Concepts
Cancer cellApoptosisCytotoxic T cellOxidative stressLung cancerCancer researchCancerChemistryProgrammed cell deathCellDNA fragmentationMedicinePathologyBiochemistryIn vitroInternal medicineMetal-Catalyzed Oxygenation MechanismsGlutathione Transferases and PolymorphismsFree Radicals and Antioxidants