Enhancing CRISPR/Cas-mediated electrochemical detection of nucleic acid using nanoparticle-labeled covalent organic frameworks reporters
Hui Qian, Xiaopeng Guo, Hongying Yang, Ting Bao, Zhen Wu, Wei Wen, Xun Zhang, Shengfu Wang
Topics & Concepts
Trans-activating crRNACRISPRAptamerNanocarriersNucleic acidDetection limitBiosensorDeoxyribozymeMolecular beaconDNAChemistryCombinatorial chemistryNanotechnologyCovalent bondAnalyteNanoparticleMaterials scienceOligonucleotideCas9Molecular biologyBiochemistryChromatographyBiologyOrganic chemistryGeneAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 detection and testingElectrochemical Analysis and Applications