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Electrosynthesis of 2,5-furandicarboxylic acid from 5-hydroxymethylfurfural: mechanisms, advanced catalysts, and reaction microenvironments

Jiacheng Zhang, Siping Wang, Jiaqing Liu, Jiayi Chen, Guigang Zhang, Yidong Hou, Meifang Zheng, Sibo Wang, Xue Lu

2026Chemical Science6 citationsDOIOpen Access PDF

Abstract

oxidation. Most notably, 2,5-furandicarboxylic acid (FDCA) has emerged as a crucial sustainable alternative to fossil-based terephthalic acid for polyester production. This review provides a comprehensive analysis of the electrocatalytic oxidation of HMF to FDCA. We begin by dissecting the reaction pathways and mechanisms to clarify key kinetic steps and current bottlenecks. To establish benchmarks for the field, we summarize standard evaluation metrics that enable rigorous comparison among disparate studies. The review then systematically categorizes diverse catalyst systems and engineering strategies, with a specific focus on how reaction parameters (pH, electrolyte composition, and applied potential) dictate product selectivity. Concluding with a forward-looking perspective, we propose future directions to accelerate the development of efficient, controllable, and low-cost technologies for FDCA production.

Topics & Concepts

ElectrosynthesisTerephthalic acidBiochemical engineeringChemistryPolyesterNanotechnologyCatalysisCombinatorial chemistryComputer scienceChemical reaction engineeringElectrolyteBiomass (ecology)Process engineeringRedoxRenewable energyKey (lock)Carbon fibersOrganic chemistryGreen chemistryReusabilityRenewable resourceReaction mechanismCatalysis for Biomass ConversionMicrowave-Assisted Synthesis and ApplicationsMulticomponent Synthesis of Heterocycles