Hydrazone analogs as DNA gyrase inhibitors and antioxidant agents: Structure-activity relationship and pharmacophore modeling
Ouafa Dammene Debbih, Wissam Mazouz, Ouided Benslama, Bachir Zouchoune, Ilhem Selatnia, Rafika Bouchene, Assia Sid, Sofiane Bouacida, Paul Mosset
Topics & Concepts
PharmacophoreHydrazoneChemistryChalconeStereochemistryDPPHSchiff baseCombinatorial chemistryDNA gyraseBiological activityMolecular modelAntioxidantIn vitroOrganic chemistryBiochemistryGeneEscherichia coliSynthesis and biological activityFree Radicals and AntioxidantsMetal complexes synthesis and properties