Reconstructing the intracellular pH microenvironment for enhancing photodynamic therapy
Chaochao Wang, Peiran Zhao, Guoliang Yang, Xiaoyan Chen, Yaqin Jiang, Xingwu Jiang, Yelin Wu, Yanyan Liu, Weian Zhang, Wenbo Bu
Abstract
PA was activated by UCNP and produced H<sup>+</sup>, restructuring the intracellular pH environment and reducing TPP's aggregation to enhance PDT.
Topics & Concepts
IntracellularPhotodynamic therapyBiophysicsIntracellular pHChemistryNanotechnologyMaterials scienceBiochemistryBiologyOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesPorphyrin and Phthalocyanine Chemistry