Design, synthesis, antibacterial evaluation, and molecular modelling studies of 1,2,3-triazole-linked coumarin-vanillin hybrids as potential DNA gyrase and topoisomerase IV inhibitors
Aanchal Khanna, A Narang, Vishakha Thakur, Karanvir Singh, Nitish Kumar, Rubaldeep Kaur, Megha, Alok Raj, Meenakshi Devi, Jyoti Jyoti, Rupali Rana, Anchal Sharma, Harmandeep Kaur, Prabhpreet Singh, Sukhraj Kaur, Preet Mohinder Singh Bedi
Topics & Concepts
DNA gyraseChemistryTopoisomeraseCoumarinVanillinTriazoleDNACombinatorial chemistryBiochemistryEnzymeStereochemistryGeneOrganic chemistryEscherichia coliSynthesis and biological activitySynthesis and Biological EvaluationPhenothiazines and Benzothiazines Synthesis and Activities