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RVDB-prot, a reference viral protein database and its HMM profiles

Thomas Bigot, Sarah Temmam, Philippe Pérot, Marc Éloit

2020F1000Research77 citationsDOIOpen Access PDF

Abstract

We present RVDB-prot, a database corresponding to the protein equivalent of the nucleic acid reference virus database RVDB. Protein databases can be helpful to perform more sensitive protein sequence comparisons. Similarly to its homologous public repository, RVDB-prot aims to provide reliable and accurately annotated unique entries, while including also an Hidden Markov Model (HMM) protein profiles database for distant protein searching.

Topics & Concepts

Hidden Markov modelUniProtDatabaseSequence databaseProtein sequencingSequence (biology)Reference databaseComputational biologyBiologyComputer sciencePeptide sequenceGeneticsArtificial intelligenceGeneBacteriophages and microbial interactionsGenomics and Phylogenetic StudiesRNA and protein synthesis mechanisms