Dual functional therapeutics: mitigating bacterial infection and associated inflammation
Yash Acharya, Kashish Kumar Taneja, Jayanta Haldar
Abstract
they have immunomodulatory properties along with the desired antibacterial activity. The classes of antibiotics that have immunomodulatory function in addition to antibacterial activity have been reviewed. Host defense peptides and their synthetic mimics are amongst the most sought-after solutions to develop such dual-functional therapeutics. This review also highlights the important classes of peptidomimetics that exhibit both antibacterial and immunomodulatory properties.
Topics & Concepts
InflammationImmune systemAntibioticsAntimicrobialImmunologySepsisMedicineInnate immune systemBiologyMicrobiologyAntimicrobial Peptides and ActivitiesPediatric health and respiratory diseasesNeuropeptides and Animal Physiology