Identification of Selective PPAR-γ Modulators by Combining Pharmacophore Modeling, Molecular Docking, and Adipogenesis Assay

Yunwei Li, Nagashree Ks, Gowramma Byran, Praveen Thaggikuppe Krishnamurthy

2022Applied Biochemistry and Biotechnology23 citationsDOI

Topics & Concepts

AdipogenesisRosiglitazonePartial agonistPharmacophorePioglitazonePharmacologyPeroxisome proliferator-activated receptorAgonistChemistryReceptorInternal medicineEndocrinologyType 2 diabetesDiabetes mellitusMedicineBiochemistryIn vitroPeroxisome Proliferator-Activated ReceptorsAdipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases