Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development
Juliette Roels, Anna Kuchmiy, Matthias Decker, Steven Strubbe, Marieke Lavaert, Kai Ling Liang, Georges Leclercq, Bart Vandekerckhove, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon
Topics & Concepts
ChromatinBiologyEpigeneticsT-cell receptorThymocyteCellular differentiationCD8EffectorLineage (genetic)Bivalent chromatinT cellNegative selectionGeneCell biologyGeneticsChromatin remodelingAntigenGenomeImmune systemImmune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy research