Dual targeting of SREBP2 and ERRα by carnosic acid suppresses RANKL-mediated osteoclastogenesis and prevents ovariectomy-induced bone loss
Zu‐Guo Zheng, Huimin Cheng, Yaping Zhou, Si-Tong Zhu, Pyone Myat Thu, Hui‐Jun Li, Ping Li, Xiaojun Xu
Topics & Concepts
ChemistryRANKLCoactivatorBone resorptionUbiquitin ligaseCell biologyInternal medicineEndocrinologyOsteoclastOsteoporosisBone remodelingActivator (genetics)ReceptorUbiquitinTranscription factorCancer researchBiochemistryBiologyMedicineGeneRetinoids in leukemia and cellular processesEstrogen and related hormone effectsPeroxisome Proliferator-Activated Receptors