Increased plasma trimethylamine-<i>N</i>-oxide levels are associated with mild cognitive impairment in high cardiovascular risk elderly population
Nida Buawangpong, Kanokporn Pinyopornpanish, Arintaya Phrommintikul, Nathamol Chindapan, Sakamon Devahastin, Nipon Chattipakorn, Siriporn C. Chattipakorn
Abstract
0.046), when adjusted for age, gender, health care service scheme, smoking history, metabolic syndrome, and history of established CV events. The high TMAO level was associated with MCI, after adjustment for potential confounding factors. These findings demonstrate that plasma TMAO levels can serve for target prediction as an independent risk factor for MCI in this population.
Topics & Concepts
Trimethylamine N-oxideCognitive impairmentBiomarkerInternal medicineCognitionMedicineTrimethylaminePopulationDiseaseEndocrinologyPsychiatryEnvironmental healthBiologyBiochemistryDementia and Cognitive Impairment ResearchNutritional Studies and DietCardiovascular Health and Risk Factors