Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative study
Hope S. Rugo, Florence Lerebours, Eva Ciruelos, Pamela Drullinsky, Manuel Ruíz‐Borrego, Patrick Neven, Yeon Hee Park, Aleix Prat, Thomas Bachelot, Dejan Juric, Nicholas C. Turner, Nickolas A. Sophos, Juan Pablo Zarate, Christina Arce, Yu-Ming Shen, Stuart Turner, Hemanth Kanakamedala, Wei‐Chun Hsu, Stephen Chia
Topics & Concepts
FulvestrantMedicineAromatase inhibitorInternal medicineOncologyBreast cancerCancerCohortRegimenClinical endpointClinical trialEstrogen receptorAromataseAdvanced Breast Cancer TherapiesPI3K/AKT/mTOR signaling in cancerCancer-related Molecular Pathways