Litcius/Paper detail

Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative study

Hope S. Rugo, Florence Lerebours, Eva Ciruelos, Pamela Drullinsky, Manuel Ruíz‐Borrego, Patrick Neven, Yeon Hee Park, Aleix Prat, Thomas Bachelot, Dejan Juric, Nicholas C. Turner, Nickolas A. Sophos, Juan Pablo Zarate, Christina Arce, Yu-Ming Shen, Stuart Turner, Hemanth Kanakamedala, Wei‐Chun Hsu, Stephen Chia

2021The Lancet Oncology350 citationsDOI

Topics & Concepts

FulvestrantMedicineAromatase inhibitorInternal medicineOncologyBreast cancerCancerCohortRegimenClinical endpointClinical trialEstrogen receptorAromataseAdvanced Breast Cancer TherapiesPI3K/AKT/mTOR signaling in cancerCancer-related Molecular Pathways