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Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development

Xinhe Zheng, Boli Wu, Yuejia Liu, Sean Simmons, Kwanho Kim, Grace S. Clarke, Abdullah Ashiq, Joshua Park, Jiwen Li, Zhilin Wang, Liqi Tong, Qizhao Wang, Keerthi Thirtamara Rajamani, Rodrigo Muñoz-Castañeda, Shang Mu, Tianbo Qi, Yunxiao Zhang, Zi Chao Ngiam, Naoto Ohte, Carina Hanashima, Zhuhao Wu, Xiangmin Xu, Joshua Z. Levin, Xin Jin

2024Cell67 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCell typeEmbryonic stem cellTranscriptomeComputational biologyTropismIn vivoCRISPRReprogrammingCellPhenotypeCell biologyEx vivoGeneMassively parallelFunction (biology)NeuroscienceGeneticsGene expressionComputer scienceParallel computingVirusCRISPR and Genetic EngineeringSingle-cell and spatial transcriptomicsViral Infections and Immunology Research
Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development | Litcius