Current role of nanoparticles in the treatment of lung cancer
Eliseo Carrasco-Esteban, José Antonio Domínguez-Rullán, Patricia Barrionuevo-Castillo, Lira Pelari-Mici, O. Leaman, Sara Sastre-Gallego, Fernando López‐Campos
Abstract
BACKGROUND: Worldwide, lung cancer is one of the leading causes of cancer death. Nevertheless, new therapeutic agents have been developed to treat lung cancer that could change this mortality-rate. Interestingly, incredible advances have occurred in recent years in the development and application of nanotechnology in the detection, diagnosis, and treatment of lung cancer. AIM: Nanoparticles (NPs) have the ability to incorporate multiple drugs and targeting agents and therefore lead to an improved bioavailability, sustained delivery, solubility, and intestinal absorption. RELEVANCE FOR PATIENTS: This review briefly summarizes the latest innovations in therapeutic nanomedicine in lung cancer with examples on magnetic, lipid, and polymer NP. Emphasis will be placed on future studies and ongoing clinical trials in this field.